Risk of Development of Diabetes in PCOS

The PCOD or polycystic ovarian disease is a disorder related to the endocrine system that happens to many women every year. The small fluid sacs develop over the ovary that may interrupt the ovulation process, cause irregularity in periods, and can cause infertility.

The excess growth of facial hair and menstrual cycle disturbance also can take place in women suffering from PCOD. If a woman remains untreated for a long time, she may have some other complications and get severe health-related problems.

However, the exact health issues related to PCOD are not known. So, does that mean that PCOD condition is dangerous for women? Well, not precisely! PCOD is not too dangerous for women, and it depends upon the way a woman is treating it and the severity of the symptoms.

Some of the Common Facts about PCOD

Here are some of the facts that tell us about PCOD and its risk.
• PCOD is the most common disorder related to hormonal disturbance and affects every 8 out of 20 women.
• It is likely to develop with prolonging medication like diabetic medicines, insulin, medicines for high cholesterol, heart disease, and high blood pressure.
• Women having type 2 diabetes and of age above 40 are at a higher risk of PCOD.
• Nearly 70% of ovulatory problems and fertility issues arise due to PCOD.
• PCOD is not too dangerous and can be treated if diagnosed earlier.

Risk Factors Associated with PCOD

Earlier, PCOD was thought to be genetic, and people have the misconception that this condition is transferred from genes of the mother. Moreover, people believed that this is one of the main risks of the disease.
However, later this thing was proven wrong because PCOD is related to hormone disbalance and is often caused due to regular uptake of insulin and other medicines for a long time. So, women with health issues like diabetes are at greater risk of PCOD.
Some research also shows that women having PCOD have the risk of low-grade inflammation that further stimulates the production of a maleic hormone known as androgen in women.

Other Health Risks Associated with PCOD

Several other health risks associated with the PCOD are as follows:
Type 2 diabetes: Prolong consumption of PCOD medicines and PCOD can also cause type 2 diabetes, and can lead to a greater risk of developing insulin resistance in the body.

Infertility: The fluid-filled sacs in the ovary prevent ovulation, and affect the fertility rate in women. The possibility is there that PCOD might lead to infertility if remained untreated for a long time.

Obesity: PCOD is also responsible for gaining weight and causing obesity in women, though that might not be the case always..
Metabolic Syndrome: Metabolic rate of a woman can also be disturbed when she suffers from PCOD. The imbalance in the hormone level in the blood also affects the body’s metabolism and causes severe health issues.

Women with PCOD are at a greater risk of gestational diabetes, endometrial cancer, heart attack, and high blood pressure. Moreover, it also leads to miscarriage if a woman conceives with PCOD.

However, these cysts are not harmful if treated earlier, and hormonal balance is achieved. Women with PCOD often experience acne issues, access hair growth on facial region, and obesity. Body inflammation is another risk associated with the PCOD that women have when they suffer from hormonal imbalance.

Final Thoughts

Women who have PCOD must deal with these health-related issues. However, that doesn’t mean that the PCOD is that dangerous. If one can treat it on time, then there is a lesser risk of these health issues.
Moreover, if you maintain a diet, take proper medication, and manage a healthy weight, you will be able to treat the disease and achieve a healthy life.
Furocyst is a natural supplement for the management of PCOS and is a clinically evaluated and patented product for the same. It has no known side effects.

References
1. https://www.medicalnewstoday.com/articles/265309#:~:text=The%20cysts%20are%20not%20harmful,growth%2C%20acne%2C%20and%20obesity.
2. https://www.columbiaindiahospitals.com/health-articles/what-polycystic-ovarian-disease-pcod-causes-treatment
3. https://www.webmd.com/women/complications-pcos
4. https://www.indiraivf.com/pcod-causes-symptoms-treatment/
5. https://www.healthline.com/health/polycystic-ovary-disease

Risk of Development of Diabetes: POLYCYSTIC OVARY SYNDROME (PCOS)

It is a condition in which hormonal imbalance in females causes the cyst formation in the ovaries. It is categorized as a major cause of infertility in females.

CYST FORMATION IN OVARIES

Ovaries in females have follicles, which are tiny, fluid-filled sacs that hold the eggs. In normal condition, when an egg gets completely matured, the follicle releases the egg so that it can travel to the uterus for fertilization.

But in women with PCOS, immature follicles bunch together to form large cysts or lumps and the eggs mature within the bunched follicles, but the follicles don’t break open to release them.

As a result, women with PCOS often don’t have menstrual periods or only have periods on occasion. Because the eggs are not released, most have trouble getting pregnant.

CONSEQUENCES OF PCOS

PCOS is a complex disease with long-term consequences. Women with PCOS have to face number of metabolic and other implications. These women are at increased risk of developing:

Diabetes
Cardiovascular disease
Hypertension
Dyslipidemia
Endometrial cancer
Ovarian cancer
Breast cancer

CONNECTION TO DIABETES

It is reported that any woman suffering from PCOS is at an increased risk of diabetes. Thus, sometimes diabetes becomes one of the diagnosis parameter of PCOS.

The prevalence of type 2 diabetes in women with PCOS is 7 times higher than other women. This Risk of Development of Diabetes increases to a much higher extent if the women are suffering from obesity too.

In women with PCOS, insulin resistance is the reason behind type 2 diabetes. The disturbed hormonal levels in PCOS interfere in the functioning of β-cells in pancreas. When β-cells get disturbed, they produce impaired amount of insulin which leads to insulin resistance. During insulin resistance, insulin does not work the way it should be. The insulin becomes unable to attach itself upon the insulin receptor site on cells. Due to this, the transfer of blood sugar from blood stream to cell is inhibited. Thus, sugar levels in the blood rises and causes type 2 diabetes.

High insulin levels in blood also reduce the fat breakdown and thus, fat starts to accumulate in the storage units/cells. This causes high cholesterol levels in the body and thus, obesity. This gives rise to more complex form of PCOS.

OUTCOMES OF DIABETES IN PCOS

If diabetes develops in PCOS suffering females, they give rise to following conditions:

Hyperandrogenism
Reproductive disorders
Acne
Hirsutism

These complications worsen the condition of PCOS.

TREATMENT STRATEGIES

It has been reported that fenugreek is an effective remedy to treat PCOS patients. It is clinically proven safe and effective in the management of PCOS. It has been observed that Furocyst (fenugreek seed extract) significantly reduced the cyst size, showed complete dissolution of the cysts and reported regular menstrual cycle on completion of the treatment. It also increased insulin sensitizing activity & peripheral utilization of insulin thus helped to manage PCOS.

Regular exercise can reduce the Risk of Development of Diabetes. It is important for keeping the body healthy, especially when it comes to fighting obesity and type 2 diabetes and it has been shown to reduce the symptoms associated with PCOS. Exercise also helps the body to burn excess blood sugar and makes the cells more sensitive to insulin, allowing the body to use insulin more effectively.

A balanced diet that provides whole grains, lean proteins, healthy fats and plenty of fruits and vegetables is a key to reduce the risk of diabetes and manage weight in PCOS females.

Insulin resistance plays a key role in the pathophysiology of this syndrome and thus, use of oral anti-diabetic drugs becomes important. The majority of studies have shown the reduction in the symptoms such as hyperandrogenism and cycle irregularities following the use of oral anti-diabetic drugs.

Women with PCOS are also treated with birth control pills, which helps to regulate menstruation and clear acne.

Women with PCOS have been shown to have higher levels of advanced glycation end products (AGEs) in their blood. AGEs are compounds formed when glucose binds with proteins, and are believed to contribute to certain degenerative diseases and aging. One small studyhas found that lowering dietary AGEs reduce insulin levels in women with PCOS.

Other treatment strategies include:

Androgen-blocking medications
Topical anti-hair-growth medications
Other excess hair treatments
Treatments for hair loss
Acne treatments
Removal of other skin problems

REFERENCES

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